Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824281 | 0.92 | CHRM2 (0.51) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL10641680 | 0.91 | CHRM2 (0.61) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9825398 | 0.91 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9824382 | 0.90 | CHRM2 (0.58) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9824387 | 0.89 | CHRM2 (0.64) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9824870 | 0.88 | CHRM2 (0.51) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9825421 | 0.83 | CHRM2 (0.61) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9824282 | 0.83 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9824290 | 0.83 | CHRM2 (0.59) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9824168 | 0.82 | CHRM2 (0.55) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |