Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824627 | 1.00 | SLC2A1 (0.50) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL9824526 | 1.00 | SLC2A1 (0.50) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL10759050 | 0.88 | SLC2A1 (0.49) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL9824630 | 0.88 | SLC2A1 (0.49) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL9824503 | 0.88 | SLC2A1 (0.49) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL9824522 | 0.87 | SLC2A1 (0.48) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9824621 | 0.87 | SLC2A1 (0.48) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9824367 | 0.87 | SLC2A1 (0.48) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL9824218 | 0.87 | SLC2A1 (0.48) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 | |
| SCHEMBL9825013 | 0.85 | CYP1A1 (0.44) | SLC2A1CYP1A2CYP1A1CYP1B1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250254-A1 | Cis & trans stilbenes and their composition for the treatment of hypertension | McNeilab, Inc. (US) | 1987-12-23 | — | — | EP | claimed |
| EP-0250254-B1 | CIS & TRANS STILBENES AND THEIR COMPOSITION FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1991-06-19 | — | — | EP | disclosed |
| EP-0250254-A1 | Cis & trans stilbenes and their composition for the treatment of hypertension | McNeilab, Inc. (US) | 1987-12-23 | — | — | EP | disclosed |