Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826185 | 1.00 | HTT (0.48) | HTTALOX5HTR1AADRA2ADRD1 | |
| SCHEMBL9825132 | 1.00 | HTT (0.48) | HTTALOX5HTR1AADRA2ADRD1 | |
| SCHEMBL9826195 | 1.00 | HTT (0.48) | HTTALOX5HTR1AADRA2ADRD1 | |
| SCHEMBL9692523 | 1.00 | HTT (0.48) | HTTALOX5HTR1AADRA2ADRD1 | |
| SCHEMBL9824754 | 0.84 | HTT (0.46) | HTTALOX5HTR1A | |
| SCHEMBL9825951 | 0.84 | HTT (0.46) | HTTALOX5HTR1A | |
| SCHEMBL9825683 | 0.82 | HTT (0.48) | HTTHTR1A | |
| SCHEMBL9692391 | 0.78 | HTT (0.48) | HTTHTR1AADRA1A | |
| SCHEMBL9692374 | 0.78 | HTT (0.48) | HTTHTR1AADRA1A | |
| SCHEMBL9692630 | 0.78 | HTT (0.46) | HTTHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |