Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.64 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20371020 | 0.86 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1PKMTHRB | |
| SCHEMBL28461478 | 0.86 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1PKMTHRB | |
| SCHEMBL3040974 | 0.85 | CYP4F2 (0.68) | CYP4F2CYP4A11ALDH1A1PKMTHRB | |
| SCHEMBL6254544 | 0.85 | CYP4F2 (0.85) | CYP4F2CYP4A11ALDH1A1PKMTHRB | |
| SCHEMBL6257314 | 0.85 | CYP4F2 (0.85) | CYP4F2CYP4A11ALDH1A1PKMTHRB | |
| SCHEMBL17756701 | 0.84 | CYP4F2 (0.83) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL17746737 | 0.84 | CYP4F2 (0.66) | CYP4F2CYP4A11ALDH1A1PKMTHRB | |
| SCHEMBL17746745 | 0.84 | CYP4F2 (0.71) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL17746731 | 0.84 | CYP4F2 (0.71) | CYP4F2CYP4A11PKMTHRBHTT | |
| SCHEMBL17756696 | 0.83 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1PKMTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111997-B1 | VINYL CARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4518602-A | Vinyl carboxylic acid derivatives, their production and use as inhibitors of thromboxane synthetase | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-05-21 | — | — | US | disclosed |
| EP-0111997-A2 | Vinyl carboxylic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-06-27 | — | — | EP | disclosed |