Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825399 | 0.95 | CYP3A4 (0.70) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL9825351 | 0.85 | POLB (0.59) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL10721329 | 0.85 | POLB (0.69) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL9714256 | 0.81 | POLB (0.68) | POLBCYP3A4CYP2C9ABCB1 | |
| SCHEMBL9825356 | 0.81 | CYP3A4 (0.65) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL9714506 | 0.79 | HPGD (0.78) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| Rh-5849 SCHEMBL1538531 | 0.79 | POLB (1.00) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL8178344 | 0.78 | ABCB1 (0.84) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL8174583 | 0.78 | POLB (0.75) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 | |
| SCHEMBL9714587 | 0.78 | ABCB1 (0.80) | POLBCYP3A4CYP2C9ABCB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |