Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844212 | 0.74 | PLA2G10 (0.39) | — | |
| SCHEMBL14886177 | 0.72 | CYP2A6 (0.52) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH | |
| SCHEMBL21524082 | 0.72 | CYP2A6 (0.47) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH | |
| SCHEMBL18783296 | 0.71 | CYP2A6 (0.50) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH | |
| SCHEMBL722595 | 0.70 | CYP2A6 (0.56) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH | |
| SCHEMBL2115254 | 0.68 | CYP2A6 (0.47) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH | |
| SCHEMBL3730275 | 0.67 | KDM4E (0.42) | CYP2A6CYP3A4CYP2B6NISCHCYP2C9 | |
| SCHEMBL4904752 | 0.67 | PDPK1 (0.41) | CYP2A6ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9825710 | 0.67 | CYP3A4 (0.42) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH | |
| SCHEMBL11613197 | 0.65 | CYP2A6 (0.45) | CYP2A6CYP3A4CYP2C19CYP2B6NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0165753-B1 | HERBICIDAL THIOPHENESULFONAMIDES AND PYRIDINESULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0441718-A1 | Herbicidally active triazolopyridine compounds | RHONE-POULENC AGROCHIMIE (FR) | 1991-08-14 | — | — | EP | disclosed |
| US-4723988-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-09 | — | — | US | disclosed |
| US-4684393-A | PLATN GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0165753-A2 | Herbicidal thiophenesulfonamides and pyridinesulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-12-27 | — | — | EP | disclosed |