Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825287 | 0.88 | TNF (0.51) | PIK3CDPIK3CBPIK3CGKDRIDO1 | |
| SCHEMBL9826722 | 0.81 | PRKCI (0.43) | PIK3CDPIK3CBPIK3CGKDRTLR8 | |
| SCHEMBL20095043 | 0.80 | KDR (0.56) | PIK3CDPIK3CBPIK3CGKDRTNF | |
| SCHEMBL9824842 | 0.79 | PPARG (0.40) | CYP1A2CYP3A4KDM4E | |
| SCHEMBL1102537 | 0.76 | TNF (0.46) | KDRIDO1TNFTLR8TLR7 | |
| SCHEMBL9824826 | 0.75 | TNF (0.58) | PIK3CDPIK3CBPIK3CGTNFNTSR1 | |
| SCHEMBL12263209 | 0.74 | AKR1C3 (0.51) | KDRTLR8TLR7IKBKETBK1 | |
| SCHEMBL28784991 | 0.73 | KDM4E (0.50) | KDRTNFIKBKETBK1CYP1A2 | |
| SCHEMBL17343237 | 0.72 | PIK3CD (0.47) | PIK3CDPIK3CBPIK3CGKDRTNF | |
| SCHEMBL1102468 | 0.72 | CYP17A1 (0.46) | KDRIDO1TNFTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |