SCHEMBL9826210

SCHEMBL9826210

CC[S+]([O-])c1ncc(C#N)s1

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDR P35968 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9827037 0.87 KDR (0.31) KDR
SCHEMBL9827143 0.84 KDR (0.30) KDR
SCHEMBL9826220 0.80 KDR (0.35) KDR
SCHEMBL11392114 0.68
SCHEMBL9864883 0.66
SCHEMBL2693418 0.65
SCHEMBL9826292 0.63 KDR (0.33) KDR
SCHEMBL1237780 0.62
SCHEMBL21515192 0.62 AR (0.34)
SCHEMBL17754096 0.61 CYP2A6 (0.44) KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301613-B1 THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1991-07-10 EP disclosed
US-4889863-A NONPHYTOTOXIC; SEEDS, SOILS DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1989-12-26 US disclosed
EP-0301613-A1 Thiazole compounds having fungicidal activity DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1989-02-01 EP disclosed