Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286608 | 0.85 | TDP1 (0.46) | TDP1TSHRPRKCAARGAA | |
| SCHEMBL6485608 | 0.85 | TDP1 (0.46) | TDP1TSHRPRKCAARGAA | |
| SCHEMBL11001848 | 0.83 | TDP1 (0.50) | TDP1TSHRPRKCAARGAA | |
| Triacetin SCHEMBL9370360 | 0.81 | TSHR (0.61) | TDP1TSHRPRKCAARGAA | |
| Triacetin SCHEMBL3870 | 0.81 | TDP1 (0.56) | TDP1TSHRPRKCAARGAA | |
| Triacetin SCHEMBL821340 | 0.81 | TDP1 (0.56) | TDP1TSHRPRKCAARGAA | |
| SCHEMBL16577939 | 0.80 | TDP1 (0.44) | TDP1TSHRPRKCAARGAA | |
| Triacetin SCHEMBL4367394 | 0.79 | TDP1 (0.54) | TDP1TSHRPRKCAARGAA | |
| Triacetin SCHEMBL8012678 | 0.79 | TDP1 (0.54) | TDP1TSHRPRKCAARGAA | |
| Triacetin SCHEMBL31035933 | 0.79 | TDP1 (0.54) | TDP1TSHRPRKCAARGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |