Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9830083 | 0.97 | CYP3A4 (0.54) | CYP3A4BCHESMPD1TSHRMAPT | |
| SCHEMBL9828744 | 0.90 | CYP3A4 (0.42) | CYP3A4BCHESMPD1MAPTHSD17B10 | |
| SCHEMBL9828381 | 0.89 | CYP3A4 (0.53) | CYP3A4BCHESMPD1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL9831416 | 0.89 | CYP3A4 (0.41) | CYP3A4BCHESMPD1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL9828731 | 0.89 | CYP3A4 (0.52) | CYP3A4BCHESMPD1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL9830079 | 0.87 | CYP3A4 (0.43) | CYP3A4BCHESMPD1MAPTHSD17B10 | |
| SCHEMBL9829954 | 0.87 | CYP3A4 (0.55) | CYP3A4BCHESMPD1TSHRMAPT | |
| Hydrochloric Acid SCHEMBL9829955 | 0.86 | CYP3A4 (0.55) | CYP3A4BCHESMPD1TSHRMAPT | |
| Fumaric Acid SCHEMBL10672966 | 0.85 | CYP3A4 (0.51) | CYP3A4BCHETSHRMAPTMAPK1 | |
| Fumaric Acid SCHEMBL10672976 | 0.85 | CYP3A4 (0.51) | CYP3A4BCHETSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | claimed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | claimed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |