SCHEMBL9828583

SCHEMBL9828583

C=C(C)C(=O)C#CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468482 0.69
Methacrylic Acid SCHEMBL8495785 0.69 TDP1 (0.42)
SCHEMBL3117445 0.69
SCHEMBL11199307 0.69
SCHEMBL4189327 0.69
SCHEMBL141617 0.67
SCHEMBL936359 0.67
SCHEMBL27756452 0.67
SCHEMBL3397969 0.67
SCHEMBL1252799 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4806693-A REACTING ACETYLENICALLY UNSATURATED COMPOUNDS WITH CARBON MONOXIDE IN PRESENCE OF CATALYST SHELL OIL COMPANY (US) 1989-02-21 US claimed
EP-0218284-A1 Process for the preparation of unsaturated ketones SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-15 EP claimed
EP-0218284-B1 PROCESS FOR THE PREPARATION OF UNSATURATED KETONES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-08-21 EP disclosed
EP-0218283-B1 PROCESS FOR THE PREPARATION OF ESTERS OF ALPHA-ETHYLENICALLY UNSATURATED ALCOHOLS AND ALPHA-ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-11-08 EP disclosed
US-4831187-A Process for the preparation of esters of alpha-ethylenically unsaturated alcohols and alpha-ethylenically unsaturated carboxylic acids SHELL OIL COMPANY (US) 1989-05-16 US disclosed
US-4806693-A REACTING ACETYLENICALLY UNSATURATED COMPOUNDS WITH CARBON MONOXIDE IN PRESENCE OF CATALYST SHELL OIL COMPANY (US) 1989-02-21 US disclosed
US-4727195-A FROM AN UNSATURATED COMPOUND AND CARBON MONOXIDE USING A CATALYST SYSTEM OF PALLADIUM ALKANOATE, ORGANIC PHOSPHINE AND PROTONIC ACID SHELL OIL COMPANY (US) 1988-02-23 US disclosed
EP-0218284-A1 Process for the preparation of unsaturated ketones SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-15 EP disclosed
EP-0218283-A1 Process for the preparation of esters of alpha-ethylenically unsaturated alcohols and alpha-ethylenically unsaturated carboxylic acids SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-15 EP disclosed