SCHEMBL9828634

SCHEMBL9828634

CCCCOC(=O)C(C)Oc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1C=O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.46
PPARG P37231 5/20 0.46
PPARD Q03181 1/20 0.42
PPARA Q07869 1/20 0.42
MEN1 O00255 1/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.39
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
KCNH2 Q12809 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9827286 0.92 FFAR1 (0.48) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL9826940 0.88 FFAR1 (0.47) FFAR1PPARGMEN1TTRPPOX
SCHEMBL10344713 0.86 FFAR1 (0.55) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL9504832 0.86 MEN1 (0.51) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL9826732 0.86 FFAR1 (0.54) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL10646337 0.85 FFAR1 (0.49) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL10643426 0.85 FFAR1 (0.49) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL9572400 0.85 FFAR1 (0.46) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL9507509 0.85 FFAR1 (0.46) FFAR1PPARGPPARDPPARAMEN1
SCHEMBL11260317 0.84 FFAR1 (0.53) FFAR1PPARGPPARDPPARAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442172-A1 Oxime derivatives and Herbicides containing the same as an active ingredient TEIJIN LIMITED (JP) 1991-08-21 EP disclosed
EP-0433451-A1 OXIME DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS AN ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1991-06-26 EP disclosed
WO-1990001874-A1 OXIME DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS AN ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1990-03-08 WO disclosed