Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827661 | 0.94 | CYSLTR1 (0.44) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9828710 | 0.93 | CYSLTR1 (0.49) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10420729 | 0.91 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2 | |
| SCHEMBL6088549 | 0.91 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6090364 | 0.89 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL6088675 | 0.89 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7009644 | 0.87 | PDE10A (0.48) | CYSLTR1CYSLTR2 | |
| SCHEMBL9828252 | 0.87 | CYSLTR1 (0.51) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL10421112 | 0.87 | CYSLTR1 (0.50) | CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL9827383 | 0.86 | CYSLTR1 (0.57) | CYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051427-A | Antiinflammatory agents and antiallergens | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-09-24 | — | — | US | claimed |
| EP-0395697-A4 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | — | 1991-03-13 | — | — | EP | claimed |
| EP-0395697-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4 | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1990-11-07 | — | — | EP | claimed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | claimed |
| WO-1989004303-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | claimed |
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4920133-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |