⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095576 | 0.67 | — | — | |
| SCHEMBL18322504 | 0.67 | — | — | |
| SCHEMBL2754686 | 0.67 | — | — | |
| SCHEMBL9166499 | 0.67 | — | — | |
| SCHEMBL4480868 | 0.67 | — | — | |
| SCHEMBL3751940 | 0.67 | — | — | |
| SCHEMBL7422533 | 0.66 | TDP1 (0.31) | — | |
| SCHEMBL3128098 | 0.64 | — | — | |
| SCHEMBL10556453 | 0.62 | — | — | |
| SCHEMBL7265383 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235347-B1 | DIHYDROPYRIDINE LACTOLS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICAL COMPOUNDS | BAYER AG (DE) | 1991-10-09 | — | — | EP | claimed |
| EP-0258729-B1 | DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1990-04-25 | — | — | EP | claimed |
| CN-87105876-A | Dihydropyridine compounds and its production and application | — | 1988-03-23 | — | — | CN | claimed |
| US-4721719-A | Dihydropyridinelactols and their use as medicaments which influence blood sugar | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | claimed |
| EP-0235347-A2 | Dihydropyridine lactols, processes for their preparation, and their use as pharmaceutical compounds | BAYER AG (DE) | 1987-09-09 | — | — | EP | claimed |
| EP-0235347-B1 | DIHYDROPYRIDINE LACTOLS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICAL COMPOUNDS | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0258729-B1 | DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |
| US-4786641-A | HYPOGLYCEMIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-22 | — | — | US | disclosed |
| CN-87105876-A | Dihydropyridine compounds and its production and application | — | 1988-03-23 | — | — | CN | disclosed |
| EP-0258729-A2 | Dihydropyridine derivatives, process for their preparation and their use | BAYER AG (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-4721719-A | Dihydropyridinelactols and their use as medicaments which influence blood sugar | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |
| US-4721719-A | Dihydropyridinelactols and their use as medicaments which influence blood sugar | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |
| US-4721719-A | Dihydropyridinelactols and their use as medicaments which influence blood sugar | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |
| EP-0235347-A2 | Dihydropyridine lactols, processes for their preparation, and their use as pharmaceutical compounds | BAYER AG (DE) | 1987-09-09 | — | — | EP | disclosed |