Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TGM2 | P21980 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830594 | 0.99 | HTT (0.69) | HTTTGM2FOLH1KMT2AHDAC3 | |
| SCHEMBL9830472 | 0.89 | HTT (0.71) | HTTTGM2FOLH1KMT2AHDAC3 | |
| SCHEMBL9829717 | 0.88 | HTT (0.61) | HTTTGM2FOLH1KMT2ALMNA | |
| SCHEMBL2875581 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 | |
| SCHEMBL125577 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 | |
| SCHEMBL2876850 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 | |
| SCHEMBL4858734 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 | |
| SCHEMBL3287016 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 | |
| SCHEMBL4857273 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 | |
| SCHEMBL3693087 | 0.87 | HTT (0.88) | HTTTGM2FOLH1KMT2AKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |