Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25406446 | 0.80 | EPHX1 (0.50) | EPHX1ITGB3ITGA2BSMN1; SMN2HSD17B10 | |
| SCHEMBL25406448 | 0.80 | EPHX1 (0.50) | EPHX1ITGB3ITGA2BSMN1; SMN2HSD17B10 | |
| SCHEMBL5858399 | 0.79 | EPHX1 (0.53) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL16140445 | 0.78 | SMN1; SMN2 (0.50) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL20794498 | 0.78 | EPHX1 (0.52) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL31452994 | 0.78 | EPHX1 (0.52) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL5610069 | 0.77 | EPHX1 (0.58) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL6755753 | 0.77 | EPHX1 (0.58) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL11150806 | 0.76 | EPHX1 (0.50) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 | |
| SCHEMBL15057857 | 0.75 | EPHX1 (0.52) | EPHX1SMN1; SMN2HSD17B10HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |