Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | ROS1 | P08922 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30344360 | 0.89 | NT5E (0.45) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL25156382 | 0.89 | NT5E (0.45) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15488469 | 0.88 | NT5E (0.57) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL2711790 | 0.83 | NT5E (0.51) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL2711168 | 0.82 | NT5E (0.50) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL19148578 | 0.79 | NT5E (0.48) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9830025 | 0.78 | NT5E (0.50) | NT5EALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL5256820 | 0.78 | NPSR1 (0.54) | ALDH1A1KMT2AMEN1KDM4EDYRK1A | |
| SCHEMBL11831263 | 0.78 | NT5E (0.45) | NT5EALDH1A1KMT2AKDM4EMAP4K4 | |
| SCHEMBL11837223 | 0.76 | NT5E (0.51) | NT5EALDH1A1KDM4ERETCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0096214-B1 | ANTIBACTERIAL PYRIMIDINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-02-27 | — | — | EP | disclosed |
| EP-0096214-A1 | Antibacterial pyrimidine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-12-21 | — | — | EP | disclosed |