Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831579 | 0.87 | NQO2 (0.41) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL10675785 | 0.84 | MEN1 (0.46) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL9830720 | 0.83 | MEN1 (0.45) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL9830860 | 0.83 | MEN1 (0.45) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL9828736 | 0.82 | MEN1 (0.44) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL9831592 | 0.78 | MEN1 (0.41) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL9830684 | 0.75 | MEN1 (0.40) | MEN1KMT2AGAAADAMTS5ALDH1A1 | |
| SCHEMBL9830507 | 0.74 | NQO2 (0.39) | MEN1KMT2AADAMTS5ALDH1A1MAPT | |
| SCHEMBL9828953 | 0.73 | CNR1 (0.42) | GAAADAMTS5ALDH1A1MAPTKDM4E | |
| SCHEMBL9831997 | 0.73 | BCHE (0.44) | MEN1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233291-B1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4739050-A | CALCIUM ANTAGONIST, ANTICOAGULANT | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0233291-A1 | 2-ARYLBENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-08-26 | — | — | EP | disclosed |