Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TARBP2 | Q15633 | 6/20 | 0.52 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11625522 | 0.86 | IKBKB (0.57) | L3MBTL1TARBP2PDCD4KDM4EIKBKB | |
| Hydrochloric Acid SCHEMBL11621803 | 0.85 | TARBP2 (0.64) | TARBP2PDCD4KDM4EGAAIKBKB | |
| SCHEMBL2179708 | 0.85 | TARBP2 (0.64) | L3MBTL1TARBP2KDM4EGAAIKBKB | |
| SCHEMBL9832492 | 0.84 | TARBP2 (0.68) | TARBP2PDCD4KDM4EGAAIKBKB | |
| Hydrochloric Acid SCHEMBL11622676 | 0.83 | TARBP2 (0.62) | L3MBTL1TARBP2KDM4EGAAIKBKB | |
| SCHEMBL11623837 | 0.83 | HDAC6 (0.54) | L3MBTL1TARBP2PDCD4KDM4EGAA | |
| SCHEMBL6506172 | 0.83 | TARBP2 (0.58) | L3MBTL1TARBP2PDCD4KDM4EGAA | |
| Hydrochloric Acid SCHEMBL11620733 | 0.83 | TARBP2 (0.66) | TARBP2PDCD4KDM4EGAAIKBKB | |
| SCHEMBL6384893 | 0.81 | TARBP2 (0.71) | TARBP2PDCD4KDM4EIKBKBPOLB | |
| SCHEMBL11623692 | 0.81 | TARBP2 (0.80) | L3MBTL1TARBP2PDCD4KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638963-B1 | N-ACYL NITROGEN HETEROCYCLES AS LIGANDS OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS | NOVARTIS AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008157273-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |
| EP-0220573-B1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-11 | — | — | EP | disclosed |
| US-4774253-A | ETHER,-ACIDS, ESTERS OR AMIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-09-27 | — | — | US | disclosed |