⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104962 | 0.87 | — | — | |
| SCHEMBL7869283 | 0.84 | TSHR (0.44) | — | |
| SCHEMBL2092034 | 0.84 | TSHR (0.44) | — | |
| SCHEMBL29010542 | 0.84 | — | — | |
| SCHEMBL2537319 | 0.84 | — | — | |
| SCHEMBL2093506 | 0.84 | TSHR (0.44) | — | |
| SCHEMBL7873491 | 0.84 | TSHR (0.44) | — | |
| SCHEMBL98349 | 0.84 | — | — | |
| SCHEMBL180130 | 0.84 | — | — | |
| SCHEMBL40677 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4178 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894404-B | Small molecular compound with naphthylamine structure and application thereof | 杭州天玑济世生物科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118251379-A | Iron death inhibitor and use thereof | 学校法人自治医科大学 | 2024-06-25 | — | — | CN | claimed |
| CN-117957215-A | Small molecular compound with naphthylamine structure and application thereof | 杭州天玑济世生物科技有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-115232129-B | PARP1 selective inhibitor and preparation method and application thereof | 上海闻耐医药科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2023085420-A1 | FERROPTOSIS INHIBITOR AND USE THEREFOR | 学校法人自治医科大学 | 2023-05-19 | — | — | WO | claimed |
| US-20230118497-A1 | PYRAZOLE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-04-20 | — | — | US | claimed |
| CN-115894317-A | Micromolecular compound with naphthylthiophenol ether structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115894404-A | Micromolecular compound with naphthylamine structure and application thereof | 杭州天玑济世生物科技有限公司 | 2023-04-04 | — | — | CN | claimed |
| WO-2023045909-A1 | SMALL MOLECULE COMPOUNDS HAVING NAPHTHYLAMINE STRUCTURE AND APPLICATION THEREOF | 杭州天玑济世生物科技有限公司 | 2023-03-30 | — | — | WO | claimed |
| WO-1999059959-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | ASTRAZENECA AB (SE) | 1999-11-25 | — | — | WO | claimed |
| US-5518994-A | 2-arylaminopyrimidinone derivative, and herbicide and plant growth regulator | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | claimed |
| EP-0636615-A1 | 2-ARYLAMINOPYRIMIDINONE DERIVATIVE, AND HERBICIDE AND PLANT GROWTH REGULATOR | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1995-02-01 | — | — | EP | claimed |
| EP-0238259-B1 | MACROLIDE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| US-4918098-A | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1990-04-17 | — | — | US | claimed |
| EP-0238259-A1 | Macrolide compounds | AMERICAN CYANAMID COMPANY (US) | 1987-09-23 | — | — | EP | claimed |
| US-4427437-A | PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1984-01-24 | — | — | US | claimed |
| US-4125619-A | ANTITHROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1978-11-14 | — | — | US | claimed |
| US-4069323-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-17 | — | — | US | claimed |
| US-4069329-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-01-17 | — | — | US | claimed |