Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.49 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833735 | 0.92 | KMT2A (0.55) | ALDH1A1KMT2AMEN1CYP2C9LMNA | |
| SCHEMBL9833087 | 0.86 | CNR1 (0.50) | ALDH1A1KMT2AMEN1GBA1CA9 | |
| SCHEMBL9831878 | 0.86 | TBXA2R (0.51) | ALDH1A1KMT2AMEN1LMNAGBA1 | |
| SCHEMBL9834420 | 0.85 | GBA1 (0.69) | ALDH1A1KMT2AMEN1GBA1POLB | |
| SCHEMBL27163604 | 0.82 | NPY1R (0.63) | ALDH1A1KMT2AMEN1CYP2C9LMNA | |
| SCHEMBL30025907 | 0.82 | NPY1R (0.63) | ALDH1A1KMT2AMEN1CYP2C9LMNA | |
| SCHEMBL7699722 | 0.79 | KMT2A (0.68) | ALDH1A1KMT2AMEN1CYP2C9LMNA | |
| SCHEMBL9834257 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1KMT2AMEN1LMNAGBA1 | |
| SCHEMBL9832410 | 0.78 | CNR1 (0.48) | ALDH1A1KMT2AMEN1LMNAGBA1 | |
| SCHEMBL9834810 | 0.77 | GBA1 (0.65) | ALDH1A1KMT2AMEN1GBA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1015711-B | Cycloalkaho [1,2-b] indole-sulphonamides | BAYER AG (DE) | 1992-03-04 | — | — | CN | disclosed |
| EP-0242518-B1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1991-04-10 | — | — | EP | disclosed |
| US-4988820-A | Inhibiting platelet aggregation, anticoagulants, thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
| US-4965258-A | Anticoagulant; thromboxane a2 antagonist | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4904797-A | REACTING A (BENZENESULFONAMIDOALKYL)CYCLOALKANO(1,2-B)INDOLE WITH ACRYLONITRILE; HYDROLYSIS, HYDROGENATION, REDUCTION | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | disclosed |
| US-4827032-A | INTERMEDIATES FOR ANTICOAGULANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0242518-A1 | Cycloalkano[1,2-b]indole-sulfonamides | BAYER AG (DE) | 1987-10-28 | — | — | EP | disclosed |
| CN-87100773-A | Cycloalkanes is [1,2-b] indoles-sulfamide compound also | — | 1987-09-02 | — | — | CN | disclosed |