Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.72 |
| ▸ | REN | P00797 | 12/20 | 0.62 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9482833 | 1.00 | KLK5 (0.72) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL6873021 | 0.90 | KLK5 (0.71) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL8787243 | 0.90 | KLK5 (0.71) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL9815894 | 0.90 | KLK5 (0.71) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL9832414 | 0.90 | KLK5 (0.71) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL6653213 | 0.89 | KLK5 (0.68) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL10606303 | 0.89 | KLK5 (0.68) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL6876159 | 0.89 | KLK5 (0.68) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL7392856 | 0.87 | KLK5 (0.67) | KLK5RENPSEN1PSEN2APH1B | |
| SCHEMBL11020393 | 0.86 | KLK5 (0.58) | KLK5RENPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026642-A | Process for the enzymatic production of ketones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-06-25 | — | — | US | disclosed |