⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanoacetamide SCHEMBL28053682 | 0.75 | — | — | |
| Cyanoacetamide SCHEMBL163613 | 0.75 | — | — | |
| Cyanoacetamide SCHEMBL28147655 | 0.73 | — | — | |
| Cyanoacetamide SCHEMBL28275993 | 0.73 | — | — | |
| Cyanoacetamide SCHEMBL28010329 | 0.73 | MCL1 (0.94) | — | |
| Cyanoacetamide SCHEMBL6468705 | 0.73 | — | — | |
| Cyanoacetamide SCHEMBL9555403 | 0.73 | — | — | |
| SCHEMBL4784948 | 0.73 | — | — | |
| Cyanoacetamide SCHEMBL28248874 | 0.73 | — | — | |
| Cyanoacetamide SCHEMBL28064393 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372470-A3 | NOVEL ALPHA-CYANO-BETA-OXOPROPIONAMIDES | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| EP-0372470-A2 | Novel alpha-cyano-beta-oxopropionamides | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | disclosed |
| EP-0372470-A2 | Novel alpha-cyano-beta-oxopropionamides | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | disclosed |
| US-4088673-A | Process for the preparation of styryl dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3987026-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |