Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL981160 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL983066 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL984101 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL983509 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL352238 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL983492 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL983517 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL982346 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL982551 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 | |
| SCHEMBL983734 | 1.00 | TSHR (0.40) | TSHRTHRBLPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429393-B2 | Graft polymer | BRIDGESTONE CORPORATION (JP) | 2008-09-30 | — | — | US | claimed |
| US-20030130398-A1 | Soft polymeric compounds including metal oxide fillers | BRIDGESTONE CORPORATION | 2003-07-10 | — | — | US | claimed |
| US-20030130426-A1 | Method of grafting polymaleimides to alkenyl butyl rubbers | BRIDGESTONE CORP. | 2003-07-10 | — | — | US | claimed |
| US-20030091527-A1 | Graft polymer | BRIDGESTONE CORPORATION (JP) | 2003-05-15 | — | — | US | claimed |
| WO-2003016398-A1 | THERMOPLASTIC ELASTOMERS AND METHOD OF MAKING THE SAME | BRIDGESTONE CORPORATION (US) | 2003-02-27 | — | — | WO | claimed |
| WO-2002098957-A1 | POLYMER GEL INCLUDING DENDRIMERS | BRIDGESTONE CORPORATION (JP) | 2002-12-12 | — | — | WO | claimed |
| US-20020188064-A1 | Poly(alkenyl-co-maleimide) , an inorganic salt, and an extender | BRIDGESTONE/FIRESTONE RESEARCH, INC. | 2002-12-12 | — | — | US | claimed |
| WO-2002094893-A1 | CENTIPEDE IONOMERS | BRIDGESTONE CORPORATION (JP) | 2002-11-28 | — | — | WO | claimed |
| US-6403724-B1 | VIBRATION DAMPING; ALKENYL-MALEIC ANHYDRIDE COPOLYMER IMIDIZED WITH PRIMARY AMINE, A MALEATED POLYALKYLENE, AT LEAST ONE DENDRIMER, AND OPTIONALLY, AN EXTENDER. | BRIDGESTONE CORPORATION (JP) | 2002-06-11 | — | — | US | claimed |
| US-6369166-B1 | PLASTICIZED; TENSILE AND TEAR STRENGTH; ELONGATION; HIGH DAMPING; ETHYLENE-MALEIC ANHYDRIDE COPOLYMER REACTED WITH PRIMARY AMINE | BRIDGESTONE CORPORATION (JP) | 2002-04-09 | — | — | US | claimed |
| US-6359064-B1 | COMBINING POLY(ALKENYL-CO-MALEIMIDE), MALEATED POLYALKYLENE AND CROSSLINKING AGENT; REACTING TO CROSSLINK AND TO FORM A MALEATED POLYALKYLENE GRAFTED POLY(ALKENYL-CO-MALEIMIDE); COMBINING WITH WITH A POLYESTER TO PROVIDE THE ELASTOMER | BRIDGESTONE CORPORATION | 2002-03-19 | — | — | US | claimed |
| WO-2002020669-A1 | POLYESTER AND POLYALKYLENE-GRAFTED POLYMER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2002-03-14 | — | — | WO | claimed |
| US-6353054-B1 | Alkenyl-co-maleimide/diene rubber copolymers and applications | BRIDGESTONE CORPORATION (JP) | 2002-03-05 | — | — | US | claimed |
| WO-2001070822-A2 | PROCESS FOR FORMING CENTIPEDE POLYMER GELS | BRIDGESTONE CORPORATION (JP) | 2001-09-27 | — | — | WO | claimed |
| US-20010021743-A1 | Method of producing a graft copolymer | BRIDGESTONE CORPORATION (JP) | 2001-09-13 | — | — | US | claimed |
| US-6191217-B1 | REACTING POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER WITH MALEATED POLYALKYLENE AND ALKYL DIAMINE UNDER SUBSTANTIALLY DRY CONDITIONS SUFFICIENT TO FORM POLYALKYLENE GRAFTED POLY(ALKYL VINYLETHER-CO-MALEIMIDE) POLYMER | BRIDGESTONE CORPORATION (JP) | 2001-02-20 | — | — | US | claimed |
| US-6133354-A | MIXING A POLY(DIALKYLSUBSTITUTED ETHYLENE-CO-MALEIMIDE) POLYMER SUCH AS POLYISOBUTYLENE-CO-MALEIMIDE, AND PLASTICIZERS OR EXTENDERS WITHIN A NON-VULCANIZED THERMOPLASTIC ELASTOMER TO FORM A DAMPING GEL; TENSILE STRENGTH AND TEAR STRENGTH | BRIDGESTONE CORPORATION (JP) | 2000-10-17 | — | — | US | claimed |
| EP-0955319-A1 | Soft compounds derived from polypropylene grafted disubstituted ethylene-maleimide copolymers | Bridgestone Corporation (JP) | 1999-11-10 | — | — | EP | claimed |
| CN-118302407-A | Carbonyl compound, method for producing isocyanate compound, and isocyanate composition | 旭化成株式会社 | 2024-07-05 | — | — | CN | disclosed |
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030091527-A1 | Graft polymer | PARG, PARN, PCNA | TSHR 4752/4885THRB 4657/4885LPAR3 2772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.