Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743487 | 0.90 | CHRM2 (0.69) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL5171242 | 0.90 | CHRM2 (0.69) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL1549648 | 0.90 | CHRM2 (0.69) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL10574679 | 0.82 | CHRM2 (0.82) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL22784487 | 0.82 | CHRM1 (0.62) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL18098066 | 0.82 | CHRM1 (0.62) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| Oxalic Acid SCHEMBL10571388 | 0.82 | CHRM2 (0.74) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL21218778 | 0.80 | CHRNA7 (0.60) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL8556819 | 0.78 | CHRM1 (1.00) | CHRM1CHRM2CYP2D6MEN1KMT2A | |
| SCHEMBL30930208 | 0.78 | CHRM1 (1.00) | CHRM1CHRM2CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398616-A3 | Chiral synthesis for producing 1-azabicyclo[2.2.1]heptane-3-carboxylates | MERCK SHARP & DOHME LTD. (GB) | 1991-11-06 | — | — | EP | disclosed |
| EP-0398617-A3 | Process for resolving 1-azabicyclo [2.2.1]heptane-3-carboxylates | MERCK SHARP & DOHME LTD. (GB) | 1991-11-06 | — | — | EP | disclosed |
| EP-0398616-A2 | Chiral synthesis for producing 1-azabicyclo[2.2.1]heptane-3-carboxylates | MERCK SHARP & DOHME LTD. (GB) | 1990-11-22 | — | — | EP | disclosed |
| EP-0398617-A2 | Process for resolving 1-azabicyclo [2.2.1]heptane-3-carboxylates | MERCK SHARP & DOHME LTD. (GB) | 1990-11-22 | — | — | EP | disclosed |