Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119457 | 0.96 | NR5A1 (0.62) | LTA4HNR5A1CYP3A4CYP2D6TSHR | |
| SCHEMBL15106754 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL2093730 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL6745183 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL11321046 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL10878033 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL2094301 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL3092648 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL1119584 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A | |
| SCHEMBL377178 | 0.94 | NR5A1 (0.66) | LTA4HNR5A1TSHRGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348387-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2023-11-02 | — | — | US | claimed |
| EP-4146623-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2023-03-15 | — | — | EP | claimed |
| CN-115803025-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2023-03-14 | — | — | CN | claimed |
| WO-2021224864-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2021-11-11 | — | — | WO | claimed |
| EP-2426106-B1 | Piperidine and Piperazine derivatives for the treatment of tumours | MERCK PATENT GMBH (DE) | 2013-07-31 | — | — | EP | claimed |
| WO-2006103119-A2 | TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND ALSO IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-10-05 | — | — | WO | claimed |
| US-20050009912-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2005-01-13 | — | — | US | claimed |
| EP-1458671-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2004-09-22 | — | — | EP | claimed |
| US-20040138304-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2004-07-15 | — | — | US | claimed |
| US-20040063760-A1 | Sodium channel modulatiors | THERAVANCE BIOPHARMA R&D IP, LLC | 2004-04-01 | — | — | US | claimed |
| CN-1058260-C | Na -2 -(4 -nitrophenulsulfonyl) ethoxycarbonyl -amino acids | HYUNDAI PHARM IND CO LTD (KR) | 2000-11-08 | — | — | CN | claimed |
| EP-1041074-A1 | Light-sensitive 4-cyanocoumarin derivatives | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2000-10-04 | — | — | EP | claimed |
| WO-2000043415-A1 | COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2000-07-27 | — | — | WO | claimed |
| EP-0998946-A1 | Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-05-10 | — | — | EP | claimed |
| WO-2000009169-A1 | NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-02-24 | — | — | WO | claimed |
| CN-1173865-A | Na-2- (4-nitrobenzenesulfonyl) ethoxycarbonyl-amino acids | HYUNDAI PHARM IND CO LTD (KR) | 1998-02-18 | — | — | CN | claimed |
| US-4591376-A | PLANT GROWTH REGULATORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | claimed |
| EP-0126234-A2 | 1,2,3-Thiadiazol-3-in-5-ylidene ureas, their preparation and compositions as plant-growth regulators and defoliants | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | claimed |
| US-4029690-A | WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-14 | — | — | US | claimed |
| US-4029683-A | WITH A SCHIFF BASE, CHRYSANTHEMATE SYNTHESIS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348387-A1 | NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF | GBA1, GBA2, GAA | LTA4H 350/4885NR5A1 4858/4885CYP3A4 2683/4885 |
| US-20040063760-A1 | Sodium channel modulatiors | SCN1A, SCN2A, SCN1B | LTA4H 454/4885NR5A1 3444/4885CYP3A4 4631/4885 |
| US-20050009912-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A3, SLC1A1 | LTA4H 3098/4885NR5A1 1621/4885CYP3A4 971/4885 |
| US-20040138304-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A1, SLC1A3 | LTA4H 1849/4885NR5A1 2891/4885CYP3A4 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.