Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.42 |
| ▸ | KDM5A | P29375 | 8/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.42 |
| ▸ | KDM4A | O75164 | 3/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837192 | 0.84 | KDM5A (0.57) | KDM4CKDM5APHF8KDM4AMEN1 | |
| SCHEMBL5571197 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL12048764 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL28156538 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL18978503 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL25491675 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL28156546 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL21207379 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL22803309 | 0.82 | SOAT1 (0.52) | MEN1FAAHTP53CYP1A2CYP3A4 | |
| SCHEMBL21207649 | 0.80 | SOAT1 (0.53) | MEN1FAAHTP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |