Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | AOC3 | Q16853 | 13/20 | 0.59 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365383 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL9570944 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL6386471 | 0.83 | SMN1; SMN2 (0.69) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL9834676 | 0.81 | SMN1; SMN2 (0.77) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL5570311 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL4886988 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL9835060 | 0.80 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL2612387 | 0.79 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL3933173 | 0.79 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AAOC3MAOBNPC1 | |
| SCHEMBL9836892 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2KMT2AAOC3MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224919-B1 | NEW THIAZOLE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4742057-A | Antiallergic thiazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0224919-A2 | New thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-06-10 | — | — | EP | disclosed |