Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666698 | 0.82 | KMT2A (0.41) | KMT2AALOX15GAAPOLBMAPK1 | |
| SCHEMBL2586234 | 0.79 | KMT2A (0.42) | KMT2AALOX15MEN1GAAPOLB | |
| SCHEMBL31083477 | 0.79 | KMT2A (0.42) | KMT2AALOX15MEN1GAAPOLB | |
| SCHEMBL13969381 | 0.79 | KMT2A (0.42) | KMT2AALOX15POLBMAPK1PYGL | |
| SCHEMBL11415204 | 0.79 | KMT2A (0.46) | KMT2AALOX15POLBPYGLNPSR1 | |
| SCHEMBL358944 | 0.79 | CA1 (0.50) | KMT2AALOX15POLBMAPK1PYGL | |
| Hydrochloric Acid SCHEMBL839423 | 0.77 | CA1 (0.48) | KMT2AALOX15POLBMAPK1PYGL | |
| SCHEMBL15379850 | 0.76 | TDP1 (0.48) | KMT2AALOX15MEN1GAAPOLB | |
| SCHEMBL28561624 | 0.74 | HDAC1 (0.50) | GAA | |
| SCHEMBL14855435 | 0.74 | KMT2A (0.43) | KMT2AALOX15POLBPYGLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208510-B1 | 1-SUBSTITUTED OXINDOLE-3-CARBOXAMINES AS ANTIINFLAMMATORY AND ANALGESIC AGENTS | PFIZER INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| US-4791129-A | RHEUMATIC DISEASES; ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1988-12-13 | — | — | US | disclosed |
| US-4725616-A | ANTIARTHRITIC AGENTS | PFIZER INC. (US) | 1988-02-16 | — | — | US | disclosed |
| EP-0208510-A2 | 1-Substituted oxindole-3-carboxamines as antiinflammatory and analgesic agents | PFIZER INC. (US) | 1987-01-14 | — | — | EP | disclosed |
| CN-86105309-A | Oxindole-3-carbonyl amines the compound that replaces as the 1-of anti-inflammatory and anodyne | — | 1987-01-14 | — | — | CN | disclosed |