Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318484 | 0.90 | CYP3A4 (0.39) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| SCHEMBL9835436 | 0.86 | SLC6A4 (0.43) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| SCHEMBL9662300 | 0.85 | CYP3A4 (0.39) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| Sulfuric Acid SCHEMBL9216691 | 0.83 | MAP3K14 (0.36) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| SCHEMBL9664109 | 0.81 | CYP3A4 (0.38) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| SCHEMBL10885411 | 0.81 | SLC6A4 (0.44) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| SCHEMBL8804298 | 0.80 | CYP3A4 (0.43) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| SCHEMBL10877467 | 0.79 | TAAR1 (0.41) | SLC6A4LMNAPOLB | |
| SCHEMBL9662313 | 0.79 | CYP3A4 (0.37) | SLC6A4SLC6A3CYP3A4CYP2C9THRB | |
| Sulfuric Acid SCHEMBL9212923 | 0.79 | CYP3A4 (0.33) | SLC6A4SLC6A3CYP3A4CYP2C9THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126430-B1 | PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0126430-A2 | Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |