Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835967 | 1.00 | MAPT (0.46) | MAPTTP53GLACYP1A2GAA | |
| SCHEMBL10394921 | 0.87 | MAPT (0.51) | MAPTTP53GLACYP1A2GAA | |
| SCHEMBL10867563 | 0.87 | MAPT (0.42) | MAPTTP53GLACYP1A2GAA | |
| Bensulfuron Methyl SCHEMBL29368260 | 0.87 | GAA (0.51) | MAPTTP53GLACYP1A2GAA | |
| Bensulfuron Methyl SCHEMBL27491070 | 0.87 | GAA (0.51) | MAPTTP53GLACYP1A2GAA | |
| Bensulfuron Methyl SCHEMBL55028 | 0.87 | GAA (0.51) | MAPTTP53GLACYP1A2GAA | |
| Bensulfuron Methyl SCHEMBL6382944 | 0.87 | GAA (0.51) | MAPTTP53GLACYP1A2GAA | |
| Bensulfuron Methyl SCHEMBL15524972 | 0.86 | GAA (0.50) | MAPTTP53GLACYP1A2GAA | |
| SCHEMBL10524876 | 0.86 | MAPT (0.48) | MAPTTP53GLACYP1A2GAA | |
| SCHEMBL10474552 | 0.86 | MAPT (0.41) | MAPTTP53GLACYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343462-B1 | AMINOGUANIDINO AZINES | BAYER AG (DE) | 1991-12-11 | — | — | EP | disclosed |
| EP-0330959-A2 | Substituted sulphonyl amino azoles | BAYER AG (DE) | 1989-09-06 | — | — | EP | disclosed |