Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836037 | 1.00 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL9835817 | 0.81 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL9835823 | 0.81 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL10763329 | 0.79 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL9835508 | 0.76 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL9835518 | 0.76 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL10402523 | 0.76 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL10402525 | 0.76 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL8305465 | 0.74 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1GLALMNAKDM4E | |
| SCHEMBL8305462 | 0.74 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1GLALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | claimed |
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | disclosed |
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | disclosed |