Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248255 | 1.00 | CNR2 (0.66) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL28343210 | 1.00 | CNR2 (0.66) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL480301 | 1.00 | CNR2 (0.66) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| Ammonia Solution, Strong SCHEMBL28407125 | 0.98 | CNR2 (0.64) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL3758968 | 0.92 | CNR2 (0.66) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL8313083 | 0.90 | TRPV1 (0.63) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL28581151 | 0.90 | CNR2 (0.83) | CNR2TRPV1CNR1FAAHMEN1 | |
| SCHEMBL5965914 | 0.89 | CNR2 (0.82) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL29091836 | 0.87 | CNR2 (0.60) | CNR2TRPV1HSP90AA1CNR1FAAH | |
| SCHEMBL21693624 | 0.86 | CNR2 (0.58) | CNR2TRPV1HSP90AA1CNR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |