Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130469 | 0.90 | DYRK1A (0.66) | DYRK1ABCHEDRD4HRH4KDM4E | |
| SCHEMBL15759147 | 0.81 | DYRK1A (0.54) | DYRK1ABCHEDRD4CYP2A6MAOA | |
| SCHEMBL4875418 | 0.77 | BCHE (0.55) | BCHEDRD4CYP2A6MAOAMAOB | |
| SCHEMBL10202570 | 0.77 | DYRK1A (0.50) | DYRK1ABCHEDRD4CYP2A6MAOA | |
| SCHEMBL10263754 | 0.77 | DYRK1A (0.50) | DYRK1ABCHEDRD4CYP2A6MAOA | |
| SCHEMBL3341967 | 0.75 | BCHE (0.59) | DYRK1ABCHEDRD4CYP2A6MAOA | |
| SCHEMBL7119156 | 0.72 | MEN1 (0.42) | DYRK1ANPY5RKDM4EALDH1A1CYP19A1 | |
| SCHEMBL606671 | 0.72 | HRH4 (0.57) | DYRK1ABCHEDRD4NPY5RHRH4 | |
| SCHEMBL604828 | 0.72 | HRH4 (0.67) | DYRK1ADRD4HRH4TSHRKDM4E | |
| SCHEMBL13780833 | 0.70 | DYRK1A (0.66) | DYRK1ABCHEHRH4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3167178-A | — | — | None | — | — | JP | disclosed |
| JP-H03167178-A | PYRIMIDINE DERIVATIVES | NAKAYAMA TAIJI | 1991-07-19 | — | — | JP | disclosed |