Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | ATP6V1B1 | P15313 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933771 | 1.00 | CYP2A6 (0.47) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL9837467 | 1.00 | CYP2A6 (0.47) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL287241 | 0.98 | CYP2A6 (0.46) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL3699449 | 0.98 | CYP2A6 (0.46) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL16677011 | 0.98 | CYP2A6 (0.46) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL3699452 | 0.98 | CYP2A6 (0.46) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL287240 | 0.98 | CYP2A6 (0.46) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL287209 | 0.95 | CYP2A6 (0.49) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL287210 | 0.95 | CYP2A6 (0.49) | CYP2A6CYP2D6MAPTIDO1NPSR1 | |
| SCHEMBL10105480 | 0.82 | CYP2A6 (0.55) | CYP2A6CYP2D6MAPTIDO1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101723873-A | 2-aryl vinyl indole compounds | JIANGSU CHIA TAI TIANQING PHAR | 2010-06-09 | — | — | CN | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| CN-101723873-B | 2-aryl vinyl indole compounds | UNIV SHAANXI NORMAL | 2012-04-25 | — | — | CN | disclosed |
| CN-101723873-B | 2-aryl vinyl indole compounds | UNIV SHAANXI NORMAL | 2012-04-25 | — | — | CN | disclosed |
| CN-101723873-A | 2-aryl vinyl indole compounds | JIANGSU CHIA TAI TIANQING PHAR | 2010-06-09 | — | — | CN | disclosed |
| CN-101723873-A | 2-aryl vinyl indole compounds | JIANGSU CHIA TAI TIANQING PHAR | 2010-06-09 | — | — | CN | disclosed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |