Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078104 | 0.90 | HPGD (0.58) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL6820109 | 0.90 | HPGD (0.58) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL5072961 | 0.90 | HPGD (0.58) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL2283267 | 0.90 | HPGD (0.58) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL5075324 | 0.90 | HPGD (0.58) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL5332341 | 0.89 | HPGD (0.59) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL23680002 | 0.87 | HPGD (1.00) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7856948 | 0.87 | HPGD (1.00) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL1155738 | 0.87 | HPGD (1.00) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10694787 | 0.84 | HPGD (0.61) | HPGDTSHRMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295278-B1 | A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION | The Lubrizol Corporation (US) | 1991-05-08 | — | — | EP | claimed |