Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.48 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837973 | 1.00 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9836018 | 0.87 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9836022 | 0.87 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9837266 | 0.85 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9837260 | 0.85 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL10763048 | 0.80 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9269002 | 0.80 | CYSLTR1 (0.77) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL9268992 | 0.80 | CYSLTR1 (0.77) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL10402290 | 0.77 | CYSLTR2 (0.62) | CYSLTR1CYSLTR2MEN1KMT2A | |
| SCHEMBL10402289 | 0.77 | CYSLTR2 (0.62) | CYSLTR1CYSLTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | disclosed |