Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.41 |
| ▸ | PDCD4 | Q53EL6 | 5/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985173 | 0.86 | CA1 (0.42) | PDCD4CA2 | |
| SCHEMBL7296014 | 0.72 | PDCD4 (0.47) | PDCD4 | |
| Benzene SCHEMBL14691483 | 0.69 | GRIK1 (0.63) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25293689 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25293243 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25292827 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25286591 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25292005 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25295689 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| SCHEMBL25286597 | 0.69 | GRIK1 (0.68) | GRIK1GRIK2SLC1A2SLC1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059611-A | Treating psoriasis and modifying calcium homeostatis | ALLERGAN, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0369812-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |