Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31647438 | 1.00 | KDM4E (1.00) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL22312042 | 0.96 | KDM4E (0.93) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL31350749 | 0.96 | KDM4E (0.93) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL13329206 | 0.82 | KDM4E (0.70) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL19734933 | 0.81 | KDM4E (0.69) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL13329207 | 0.81 | KDM4E (0.68) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL13329199 | 0.79 | KDM4E (0.65) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL6255063 | 0.78 | KDM4E (0.64) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL4048718 | 0.77 | KDM4E (0.62) | KDM4EHTTGLAALDH1A1L3MBTL1 | |
| SCHEMBL31647935 | 0.77 | KDM4E (0.62) | KDM4EHTTGLAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134366-A1 | 3-AZABICYCLOALKYL DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Lg Chem, Ltd. (KR) | 2023-02-15 | — | — | EP | disclosed |
| EP-0124992-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-05-29 | — | — | EP | disclosed |
| US-4680400-A | Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-07-14 | — | — | US | disclosed |
| US-4640708-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-03 | — | — | US | disclosed |
| EP-0124992-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |