Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838216 | 0.83 | GAA (0.56) | NPSR1HCAR2ALDH1A1MGAMGAA | |
| SCHEMBL19438257 | 0.80 | NPSR1 (0.56) | NPSR1HCAR2ALDH1A1SMN1; SMN2MGAM | |
| SCHEMBL13296298 | 0.80 | NPSR1 (0.56) | NPSR1HCAR2ALDH1A1SMN1; SMN2MGAM | |
| SCHEMBL1300399 | 0.79 | NPSR1 (0.50) | NPSR1HCAR2ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL29156599 | 0.78 | KDM4E (0.54) | NPSR1HCAR2ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL9127380 | 0.78 | NPSR1 (0.53) | NPSR1HCAR2ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL10878721 | 0.77 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL10878727 | 0.77 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1CYP2D6SMN1; SMN2 | |
| SCHEMBL10432065 | 0.77 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1SMN1; SMN2MGAM | |
| SCHEMBL11196356 | 0.77 | NPSR1 (0.52) | NPSR1HCAR2ALDH1A1SMN1; SMN2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |