Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 7/20 | 0.64 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.64 |
| ▸ | OXTR | P30559 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713003 | 0.84 | AVPR2 (0.58) | AVPR2AVPR1AOXTR | |
| SCHEMBL8719656 | 0.83 | AVPR2 (0.66) | AVPR2AVPR1AOXTR | |
| SCHEMBL8715632 | 0.79 | AVPR2 (0.52) | AVPR2AVPR1AOXTR | |
| SCHEMBL8719606 | 0.79 | AVPR2 (0.51) | AVPR2AVPR1AOXTR | |
| SCHEMBL7351118 | 0.78 | AVPR1A (1.00) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7343665 | 0.77 | AVPR1A (0.98) | AVPR2AVPR1AOXTRAVPR1B | |
| SCHEMBL7351096 | 0.77 | AVPR2 (0.58) | AVPR2AVPR1AOXTRABCB11HTR1A | |
| SCHEMBL7351740 | 0.77 | AVPR2 (0.94) | AVPR2AVPR1AOXTR | |
| SCHEMBL8558906 | 0.77 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL8712392 | 0.74 | AVPR2 (0.70) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |