Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31170722 | 1.00 | TSHR (0.52) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983627 | 1.00 | TSHR (0.52) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL2865636 | 1.00 | TSHR (0.52) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL984314 | 1.00 | TSHR (0.52) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL109547 | 1.00 | TSHR (0.52) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL984540 | 1.00 | TSHR (0.52) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL981301 | 0.98 | TSHR (0.53) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL32668975 | 0.98 | TSHR (0.53) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL984167 | 0.93 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983265 | 0.93 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266338-B | The manufacturing method of isocyanates | 旭化成株式会社 | 2019-10-11 | — | — | CN | disclosed |
| EP-2275405-B1 | PROCESS FOR PRODUCING ISOCYANATE USING DIARYL CARBONATE | ASAHI CHEMICAL IND (JP) | 2019-04-24 | — | — | EP | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| EP-2792673-B1 | Carbamic acid ester derivatives for the production of isocyanate and aromatic hydroxy compounds | ASAHI CHEMICAL IND (JP) | 2018-07-25 | — | — | EP | disclosed |
| EP-3099654-B1 | SYNTHETIC METHOD | UNIV COURT UNIV ST ANDREWS (GB) | 2018-05-09 | — | — | EP | disclosed |
| US-9908826-B2 | Synthetic method | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-06 | — | — | US | disclosed |
| US-20170174608-A1 | Synthetic Method | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2017-06-22 | — | — | US | disclosed |
| US-9637445-B2 | Isocyanate production process using composition containing carbamic acid ester and aromatic hydroxy compound, and composition for transfer and storage of carbamic acid ester | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2017-05-02 | — | — | US | disclosed |
| EP-2147909-B1 | METHOD FOR PRODUCTION OF ISOCYANATE USING COMPOSITION COMPRISING CARBAMIC ACID ESTER AND AROMATIC HYDROXY COMPOUND, AND COMPOSITION FOR TRANSPORT OR STORAGE OF CARBAMIC ACID ESTER | ASAHI CHEMICAL IND (JP) | 2016-12-14 | — | — | EP | disclosed |
| EP-3099654-A1 | SYNTHETIC METHOD | University Court of The University of St Andrews (GB) | 2016-12-07 | — | — | EP | disclosed |
| EP-0279261-A2 | Particle-shaped multiphase polymerisates | BAYER AG (DE) | 1988-08-24 | — | — | EP | disclosed |
| EP-0272441-A2 | Polymer powder containing silicone rubber, its preparation and use as a flame-retardant additive | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0260559-A2 | Non-aging thermoplastic moulding compositions with an enhanced degree of toughness at a low temperature | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0260558-A2 | Non-aging thermoplastic moulding composition with a good degree of toughness | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0143877-B1 | STABLE SILICONE EMULSIONS | BAYER AG (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0258746-A2 | Grafted siloxane elastomers having a notch impact resistance | BAYER AG (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-4714691-A | Heterogeneous catalyst process | ETHYL CORPORATION (US) | 1987-12-22 | — | — | US | disclosed |
| EP-0217257-A2 | Diorganosiloxane polymer powder | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4631349-A | RESIN-BONDED ALUMINUM PHENOXIDE CATALYST TO ALKYLATE PHENOLS | ETHYL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0143877-A1 | Stable silicone emulsions | BAYER AG (DE) | 1985-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174608-A1 | Synthetic Method | SQLE, FDFT1, CYP51A1 | TSHR 4021/4885CYSLTR2 108/4885CYSLTR1 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.