Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837009 | 0.94 | PTAFR (0.58) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9836966 | 0.89 | PTAFR (0.64) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10513238 | 0.87 | PTAFR (0.50) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10511953 | 0.87 | PTAFR (0.51) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL10511536 | 0.84 | PTAFR (0.49) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9838474 | 0.84 | PTAFR (0.59) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL9836970 | 0.83 | PTAFR (0.58) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9837222 | 0.83 | PTAFR (0.56) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL9838502 | 0.82 | PTAFR (0.59) | PTAFROPRK1PDE4DCYP3A4ALOX15 | |
| SCHEMBL8928417 | 0.82 | PTAFR (0.66) | PTAFROPRK1PDE4DCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028603-A | Platelet-Activating Factor Antagonist; Useful In Treatment Of Inflammatory Diseases, Allergic Diseases, Asthma, Respiratory System Disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |