Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573637 | 1.00 | MAPK1 (0.31) | MAPK1 | |
| Hydrochloric Acid SCHEMBL28575505 | 0.98 | MAPK1 (0.30) | MAPK1 | |
| Hydrochloric Acid SCHEMBL7624938 | 0.98 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL7442843 | 0.95 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL22388041 | 0.91 | — | — | |
| SCHEMBL13676325 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28566347 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28564693 | 0.71 | — | — | |
| SCHEMBL5731681 | 0.70 | — | — | |
| SCHEMBL7305562 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985420-A | 5-HYDROXYTRYPTAMINE RECEPTOR ANTAGONISTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-01-15 | — | — | US | disclosed |
| EP-0350130-A2 | New substituted 1,7-annelated 1H-indazoles | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1990-01-10 | — | — | EP | disclosed |