SCHEMBL9838566

SCHEMBL9838566

COc1ccc([PH](=O)c2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
CA14 Q9ULX7 1/20 0.56
ALDH1A1 P00352 7/20 0.50
CYP1A1 P04798 7/20 0.48
CYP1A2 P05177 7/20 0.48
CYP1B1 Q16678 7/20 0.48
CYP3A4 P08684 2/20 0.48
NPC1 O15118 1/20 0.44
CYP2E1 P05181 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP4B1 P13584 1/20 0.44
CYP2B6 P20813 1/20 0.44
CYP3A5 P20815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11653467 0.86 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL13240564 0.86 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL9355708 0.84 CA12 (0.52) CA12CA1CA2CA7CA9
SCHEMBL11652778 0.78 CA12 (0.46) CA12CA1CA2CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL27777905 0.72 CA12 (1.00) CA12CA1CA2CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL481491 0.72 CA12 (1.00) CA12CA1CA2CA7CA9
1,2,4-Trimethoxybenzene SCHEMBL29350371 0.72 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL595279 0.71 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL2153848 0.71 CA1 (0.55) CA12CA1CA2CA7CA9
SCHEMBL1802326 0.71 CA12 (0.62) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110330526-B Green synthesis method of thiophosphite 成都理工大学 2021-11-26 CN disclosed
US-4985567-A Ligand for a Metal Complex Catalyst KAZUO ACHIWA (JP) 1991-01-15 US disclosed
EP-0336123-A2 New chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) 1989-10-11 EP disclosed