Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | APAF1 | O14727 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838769 | 1.00 | TDP1 (0.46) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9840475 | 0.92 | MAPT (0.45) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9840470 | 0.92 | MAPT (0.45) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9840479 | 0.92 | TDP1 (0.46) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9840495 | 0.92 | TDP1 (0.46) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9184532 | 0.85 | TDP1 (0.47) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL9183489 | 0.85 | TDP1 (0.47) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10354078 | 0.85 | MAPT (0.63) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10354076 | 0.85 | MAPT (0.63) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL8759736 | 0.84 | TDP1 (0.45) | TDP1APAF1LMNATSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073551-A | Antibiotics | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0335390-A2 | Novel cephalosporin compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-10-04 | — | — | EP | disclosed |