Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 1.00 |
| ▸ | FNTB | P49356 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 1/20 | 1.00 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chaetomellic Acid A SCHEMBL29394340 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL9839280 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL29580753 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| Chaetomellic Acid C SCHEMBL6686707 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL6692451 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL28492286 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL30119478 | 1.00 | FNTA (1.00) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL554180 | 0.98 | FNTA (0.96) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL554183 | 0.98 | FNTA (0.96) | FNTAFNTBTHRBPGGT1BGPR84 | |
| SCHEMBL1086437 | 0.91 | FNTA (0.83) | FNTAFNTBTHRBPGGT1BGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188749-B1 | DERIVATIVES OF FUMARIC ACID, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Speiser, Peter Paul, Prof. Dr. (CH) | 1991-03-06 | — | — | EP | disclosed |
| EP-0188749-A2 | Derivatives of fumaric acid, process for their preparation and pharmaceutical compositions containing them | Speiser, Peter Paul, Prof. Dr. (CH) | 1986-07-30 | — | — | EP | disclosed |