SCHEMBL9840272

SCHEMBL9840272

O=C(CCSc1ccc(O)cc1)CCSc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.59
KCNH2 Q12809 1/20 0.59
CA2 P00918 1/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C19 P33261 2/20 0.43
ALDH1A1 P00352 4/20 0.42
NR1H2 P55055 1/20 0.42
HPGD P15428 8/20 0.42
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4509079 0.92 HSP90AA1 (0.56) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL28795059 0.88 HSP90AA1 (0.53) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL28725221 0.88 HSD17B3 (0.50) HSP90AA1KCNH2NPC1RAB9AMAPT
SCHEMBL989865 0.85 HSP90AA1 (0.57) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL9485724 0.84 HSP90AA1 (0.49) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL8623830 0.83 HSP90AA1 (0.56) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL11034897 0.82 HSP90AA1 (0.54) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL10407904 0.81 NR1H2 (0.55) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL9808265 0.79 HTT (0.53) HSP90AA1KCNH2CA2NPC1RAB9A
SCHEMBL10609588 0.79 HSP90AA1 (0.51) HSP90AA1KCNH2NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116194303-A Thermosensitive recording medium 日本制纸株式会社 2023-05-30 CN disclosed
CN-102483886-B Thermosensitive recording label NIPPON PAPER INDUSTRIES CO.,LTD. (JP) 2015-10-07 CN disclosed
US-4981970-A LEUCO DYES, RECORDING RICOH COMPANY, LTD. (JP) 1991-01-01 US disclosed
US-4940691-A Coloring phthalide compounds and recording materials using the compounds as coloring component RICOH COMPANY, LTD. (JP) 1990-07-10 US disclosed
US-4880762-A OPTICAL RECORDING MEDIA RICOH COMPANY, LTD. (JP) 1989-11-14 US disclosed
US-4620205-A MULTILAYER-SUPPORT, HIGH TEMPERATURE COLOR FORMING LAYER DECOLORIZING AND LOW TEMPERATURE COLOR FORMING LAYER RICOH COMPANY, LTD. (JP) 1986-10-28 US disclosed