Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 3/20 | 0.48 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840262 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL9840244 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL9840487 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL10722658 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL10550230 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL9840807 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL9840778 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL9839420 | 1.00 | HPSE (0.48) | HPSERARBRARARARGGABRP | |
| SCHEMBL9840865 | 0.99 | HPSE (0.47) | HPSERARBRARARARGGABRP | |
| SCHEMBL10721132 | 0.97 | HPSE (0.46) | HPSERARBRARARARGGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |
| US-4834904-A | FERROELECTRIC LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |