Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 6/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | RAD1 | O60671 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LTA | P01374 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762285 | 0.87 | MIF (0.78) | MIFTRPA1TRPV1 | |
| SCHEMBL6664156 | 0.81 | MIF (0.50) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL1022395 | 0.81 | MIF (0.50) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL18398873 | 0.78 | MIF (0.62) | MIFCA1CA2ALDH1A1MAPT | |
| SCHEMBL20422083 | 0.78 | MIF (0.62) | MIFCA1CA2ALDH1A1MAPT | |
| SCHEMBL3903225 | 0.78 | P2RY6 (0.47) | MIFP2RY6CA1CA2HSD17B10 | |
| SCHEMBL1457324 | 0.78 | MIF (0.64) | MIFTRPA1TRPV1 | |
| SCHEMBL3923883 | 0.78 | MIF (0.64) | MIFTRPA1TRPV1 | |
| 1-Phenylethyl Isothiocyanate SCHEMBL3795180 | 0.77 | MIF (1.00) | MIFTRPA1TRPV1HSD17B10KDM4E | |
| 1-Phenylethyl Isothiocyanate SCHEMBL3792824 | 0.77 | MIF (1.00) | MIFTRPA1TRPV1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011861-A | Containing functional groups capable of bonding peptides and proteins | MILLIPORE CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0353460-A2 | Membranes for solid phase protein sequencing | MILLIPORE CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |